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Babies of chronic users may have difficulty in breathing and feeding, disturbed sleep patterns, sweating, irritability and fever.

The timing and severity of withdrawal issues will differ depending on the specific substance and its pharmacokinetics and pharmacodynamics.

Symptoms of dependence: tolerance resulting in higher levels needed to achieve the same calming effect.

CNS depressants should be used with other medications only under a physician's supervision.

Typically, they should not be combined with any other medication or substance that causes CNS depression, including prescription pain medicines, some over-the-counter cold and allergy medications, or alcohol.

Benzodiazepines, such as diazepam (Valium), chlordiazepoxide HCl (Librium), and alprazolam (Xanax), which can be prescribed to treat anxiety, acute stress reactions, and panic attacks; the more relaxing benzodiazepines, such as triazolam (Halcion) and estazolam (Pro Som) can be prescribed for short-term treatment of sleep disorders.

In higher doses, some CNS depressants can be used as general anesthetics.Because all CNS depressants work by slowing the brain's activity, when an individual stops taking them, the brain's workings can rebound and race out of control, possibly resulting in seizures and other harmful consequences.Although withdrawal from benzodiazepines can be a difficult experience, it is rarely life threatening, whereas withdrawal from prolonged use of other CNS depressants can have life-threatening complications.Despite their many beneficial effects, barbiturates and benzodiazepines have the potential for abuse and should be used only as prescribed.During the first few days after taking a prescribed CNS depressant, a person usually feels drowsy and uncoordinated, however this will diminish.For example, if you are taking a pain reliever for chronic pain and the medication no longer seems to be effectively controlling the pain, check with your doctor rather than increasing the dosage on your own.

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