Sedating muscle relaxant
In the head to head trial of cyclobenzaprine and carisoprodol, dry mouth was more frequent with cyclobenzaprine (38% vs. Metaxalone has the fewest reported side effects of any skeletal muscle relaxants and appears to be the safest.Metaxalone is considered to be less sedating in comparison with carisoprodol and cyclobenzaprine.Talk to your doctor about which medications may be most appropriate for you.
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The manufacturer's product labeling should always be consulted for a list of side effects most frequently appearing in patients during clinical studies.
Metaxalone is contraindicated in drug-induced, hemolytic or other anemias and in significantly impaired renal or hepatic function. When there is no a clearly superior agent, side effect profiles and cost become a significant factor in the selection of muscle relaxers.
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Carisoprodol: The action of carisoprodol is related to a central nervous system (CNS) mechanism and not to a direct effect on skeletal muscles.
Carisoprodol acts on the spinal cord and subcortical levels of the brain to depress polysynaptic neuron transmission.This review investigates the efficacy, side effects, and safety of three commonly prescribed skeletal muscle relaxants metaxalone (Skelaxin), cyclobenzaprine (Flexeril), and carisoprodol (Soma).Muscle relaxants are not really a class of drugs, but rather a group of different medications that produce an overall sedative effect on the body.Contraindications Carisoprodol is contraindicated in patients with a history of acute intermittent porphyria. The centrally acting skeletal muscle relaxants have been shown to be efficacious in the treatment of painful musculoskeletal disorders.Cyclobenzaprine is contraindicated in patients with hyperthyroidism, congestive heart failure, and other heart conductions. Studies have indicated they may be more effective in combination with analgesics.Brief history All three medications are indicated as an adjunct to rest, physical therapy, and other measures for the relief of discomforts associated with acute, painful musculoskeletal conditions.Tags: Adult Dating, affair dating, sex dating